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2026 (English)In: International Journal of Eating Disorders, ISSN 0276-3478, E-ISSN 1098-108X, Vol. 59, no 1, p. 190-204Article in journal (Refereed) Published
Abstract [en]
Objective
Maladaptive exercise (ME), problematic attitudes or behaviors related to physical activity, is often observed in eating disorders (EDs), but its prevalence, severity, and relationships with ED features remain incompletely characterized. This study aimed to describe lifetime and current ME across ED diagnoses, examine associations with ED symptoms, sociodemographic characteristics, and weight status, and compare ME phenotypes to identify those most strongly linked to ED features.
Methods
ME was assessed in 31,671 individuals with lifetime EDs (anorexia nervosa [AN], bulimia nervosa, and binge-eating disorder [BED]) recruited to sites in the United States, Australia, New Zealand, and Sweden as part of the Eating Disorders Genetics Initiative (NCT04378101). We examined one lifetime ME phenotype, capturing any occurrence of ME across the lifespan (derived from the ED100K), and five current ME phenotypes (any driven exercise [Eating Disorder Examination-Questionnaire, EDE-Q], frequency of driven exercise [EDE-Q], regular driven exercise [EDE-Q], compulsive exercise test [CET] total, and dichotomous compulsive exercise [CET]).
Results
Lifetime ME was highly prevalent across countries and ED diagnoses (pooled prevalence 88%). Current ME was also common (40% any driven exercise, 35% compulsive exercise, and 12% regular driven exercise), highest in AN and lowest, but notable, in BED. CET-based phenotypes showed the strongest association with ED symptoms, while EDE-Q-derived regular driven exercise was most strongly associated with underweight (BMI < 18.5). Younger generations exhibited a higher ME risk, likely reflecting societal shifts in body ideals and fitness culture.
Discussion
This large, multicountry study demonstrates that ME is highly prevalent across EDs, often emerges early, and can persist or recur for decades. Prevalence and severity vary considerably by assessment method. The ED100K, CET, and EDE-Q capture complementary aspects of ME, and incorporating all three may improve clinical care. We recommend that clinicians assess both current and lifetime ME in all patients with EDs. Routine, harmonized assessment will be essential to advancing research and improving patient outcomes.
Trial Registration
ClinicalTrials.gov identifier: NCT04378101
Place, publisher, year, edition, pages
John Wiley & Sons, 2026
Keywords
Eating Disorders Genetics Initiative (EDGI), compulsive exercise, eating disorders, exercise, maladaptive exercise, physical activity.
National Category
Psychiatry
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-8866 (URN)10.1002/eat.24563 (DOI)001596972500001 ()41115789 (PubMedID)2-s2.0-105019211018 (Scopus ID)
Funder
Swedish Research Council, 538‐2013‐8864Swedish Research Council, R276‐2018‐4581NIH (National Institutes of Health), UL1TR001111NIH (National Institutes of Health), UL1TR002489Swedish Society for Medical Research (SSMF), PG‐22‐0478Fredrik och Ingrid Thurings Stiftelse, 2021‐00660
Note
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
2025-11-042025-11-042026-01-12