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  • 1.
    Alfven, G
    et al.
    Karolinska Institutet.
    Grillner, S
    Karolinska Institutet.
    Andersson, Eva
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Laboratory for Biomechanics and Motor Control. Karolinska institutet.
    Review of childhood pain highlights the role of negative stress.2019In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227Article, review/survey (Refereed)
    Abstract [en]

    AIM: Recurrent pain of unknown origin is a major problem in children. The aim of the present review was to examine the hypothesis of negative stress as an aetiology of recurrent pain from different aspects.

    METHODS AND RESULTS: Epidemiological studies, clinical experience and hormonal data give support for such a hypothesis. Negative stress as a tentative aetiology for recurrent pain is reviewed. Stress, muscular tension, the startle reaction and its tentative relation to pain is illuminated. Deviations of hormonal secretion supporting a stress aetiology is mentioned. The role of central sensitization for recurrent pain is discussed. Possible aetiological implications of recurrent pain as a local symptom or a general disorder are presented. Brain changes due to stress is shortly reviewed. Stress and pain in the clinic are highlighted. The importance of biological, psychological and social factors, as well as genetic elements, are-Ddiscussed.

    CONCLUSION: Stress elicits neurobiological mechanisms. They may lead to many neurophysiological deviances. Increase of muscle tension and neuromuscular excitability and enhanced startle reaction may be of importance for recurring pain. The identification of stress as a primary cause of recurrent pain can have huge implications for understanding signs and treatment in clinical practice. This article is protected by copyright. All rights reserved.

    The full text will be freely available from 2020-06-04 12:00
  • 2.
    Björkman, Frida
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology.
    Eggers, Andrea
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology.
    Stenman, Adam
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology.
    Bohman, Tony
    Karolinska institutet.
    Ekblom, Björn
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology, Björn Ekblom's research group.
    Ekblom, Örjan
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology.
    Sex and maturity status affected the validity of a submaximal cycle test in adolescents.2018In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 107, no 1, p. 126-133Article in journal (Refereed)
    Abstract [en]

    AIM: This study assessed the validity and reliability of the Ekblom-Bak (EB) submaximal cycle test in adolescents and identified any sex- or maturity-related factors for prediction errors.

    METHODS: We recruited 50 healthy subjects through a public announcement in Stockholm, Sweden, in 2016. The 27 boys and 23 girls were aged 10-15 years and in Tanner stages I-IV. They performed an EB test and incremental treadmill running test for direct measurement of maximal oxygen uptake (VO2 max).

    RESULTS: The estimation error of VO2 max was 0.09 L/min. The correlation (r) was 0.86, and the standard error of the estimate (SEE) was 0.29 L/min. The largest overestimation was seen in prepubertal boys (0.49 L/min). The best precision of the EB test was achieved when boys in Tanner stages I and II were re-calculated using the prediction equation developed for adult women. This yielded a mean difference of -0.05 L/min, r = 0.92 and SEE 0.23 L/min, in the entire sample. The prediction error was lowered in boys, but not girls, with increasing pubertal maturity.

    CONCLUSION: The EB test was reasonably valid in adolescents, seemed to be related to sex and maturity status, and our findings support its use.

  • 3.
    Danielsen, Yngvild
    et al.
    University of Bergen, Norway.
    Júlíusson, Pétur
    University of Bergen, Norway.
    Nordhus, Inger Hilde
    Haukeland University Hospital, Bergen, Hordaland, Norway.
    Kleiven, M
    University of Bergen, Norway.
    Meltzer, H M
    Norwegian Institute of Public Health, Kristiania (historical), Oslo County, Norway.
    Olsson, Sven Johan Gustav
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology, Björn Ekblom's and Mats Börjesson's research group.
    Pallesen, S.
    The relationship between life-style and cardio-metabolic risk indicators in children: the importance of screen time2011In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 100, no 2, p. 253-259Article in journal (Refereed)
    Abstract [en]

    AIMS:

    To examine differences between children with obesity and normal weight children (aged 7-13 years) in terms of physical activity, screen time, food intake and blood parameters indicative of cardio-metabolic risk. Further, to explore the relationship between physical activity, screen time and food intake with cardio-metabolic parameters.

    METHODS:

    Forty-three children with obesity were compared with 43 normal weight peers. Physical activity was monitored by accelerometers and screen time and food intake by diaries. Blood parameters indicative of cardio-metabolic risk were analysed.

    RESULTS:

    The group of children with obesity had significantly less vigorous activity (p = 0.013), more daily screen time (p = 0.004) and consumed more fat (p = 0.04) than the group of normal weight children. The former group also demonstrated higher values of triglycerides (p = 0.001), HbA1c (p = 0.009), C-peptide (p = 0.001), had a higher HOMA-R score (p = 0.001), and lower levels of HDL (p = 0.001). After controlling for weight category, regression analyses revealed that screen time was significantly and positively related to the HOMA-R score and C-peptide levels independent of physical activity and intake of fat and sugar.

    CONCLUSIONS:

    The results indicate that screen time is an important behavioural factor related to obesity and cardio-metabolic risk indicators in children.

  • 4.
    Ekblom, Örjan
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology, Björn Ekblom's and Mats Börjesson's research group.
    Testing the validity of three submaximal ergometer tests for estimating maximal aerobic capacity in children.2014In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 103, no 5, p. 559-563Article in journal (Refereed)
    Abstract [en]

    AIM:

    Aerobic capacity in children has been linked to health-related outcomes, but the validity of existing assessment methods is largely unknown. This study evaluated the validity of the Åstrand-Rhyming, Woynarowska and Olgun Binyildiz methods.

    METHODS:

    Aerobic capacity was estimated from the heart rate response to submaximal ergometer cycling in 62 children aged 11-12 years. Direct measurement of peak oxygen consumption during a graded maximal treadmill test was used as the criterion method.

    RESULTS:

    We found low mean bias for age-adjusted Åstrand-Rhyming data and Woynarowska data, (-14 and 23 mL/min, respectively), low correlation to criterion values (0.81 and 0.74, respectively) and high standard error of estimate (SEE) (340 and 395 mL/min). The Olgun Binyildiz method gave high correlation (0.87) and low SEE (298 mL/min), but large bias (-660 mL/min). All methods underestimated capacity in well-trained children.

    CONCLUSION:

    The Olgun Binyildiz method is recommended for following an individual over time, due to its low random error. But for comparing individual data with those obtained using direct measurements, the Woynarowska or Åstrand-Rhyming method may be the first choice. However, they all underestimated aerobic capacity in well-trained children.

  • 5.
    Ekblom, Örjan B
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Bak, Elin A M Ekblom
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Ekblom, Björn T
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Cross-sectional trends in cardiovascular fitness in Swedish 16-year-olds between 1987 and 2007.2011In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 100, no 4, p. 565-9Article in journal (Refereed)
    Abstract [en]

    AIM: We sought to investigate the temporal trends in estimated maximal aerobic capacity in adolescents (mean age 16.1).

    METHODS: Analyses were based on data from three population-based samples, collected in 1987 (n=221), 2001 (n=537) and 2007 (n=265). Subjects underwent sub-maximal ergometer testing. Absolute and relative aerobic capacities were estimated using the Åstrand-Ryhming nomogram.

    RESULTS: Compared to 1987, values for estimated relative and absolute maximal aerobic capacities were lower in 2001 and 2007, and values in 2007 were lower compared to 2001, in both boys and girls, except for absolute capacity between 1987 and 2001 in girls. The differences over time did not differ between genders. Absolute values changed from 3.0 and 2.5 L/min in 1987 to 2.5 and 2.2 L/min in 2007, for boys and girls, respectively. Relative values changed from 46.5 and 45.9 mL/min/kg in 1987 to 35.0 and 36.6 mL/min/kg, in 2007, for boys and girls, respectively.

    CONCLUSION: Based on earlier reports on the relationship between aerobic capacity and metabolic risk, the results from the present study provide argument that future public health will be affected negatively.

  • 6.
    Ekblom, Örjan
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Oddsson, Kristjan
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Laboratory for Biomechanics and Motor Control.
    Ekblom, Björn
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Health-related fitness in Swedish adolescents between 1987 and 2001.2004In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 93, no 5, p. 681-6Article in journal (Refereed)
    Abstract [en]

    AIM: To assess trends in neuro-muscular and cardio-respiratory fitness and morphological fitness in Swedish adolescents between 1987 and 2001. METHODS: Comparison of data from two samples, one from 1987 (n = 479) and one from 2001 (n = 1470). Subjects underwent functional tests of muscular strength in the lower limbs, trunk and upper body, sub-maximal ergometrics, and measurement of body mass and height. RESULTS: Cardio-respiratory fitness showed only small changes between 1987 and 2001 among boys, with no changes in girls. Neuro-muscular fitness, as measured by three functional tests, was lower in 2001 compared to 1987. The most pronounced changes in these functional tests were found in the arm-hang test, while changes in lower body and trunk strength tests were less. Our results indicate that the difference in the prevalence of overweight in adolescents between 1987 and 2001 is mainly due to a large change in the most unfit group. The fittest group showed only marginal changes. CONCLUSION: We suggest that the differences in neuro-muscular fitness are at least partly due to differences in the amount and nature of physical activity, and that this might lead to consequences for health later in life.

  • 7.
    Flygare Wallén, Eva
    et al.
    Karolinska Institutet.
    Müllersdorf, Maria
    Mälardalens universitet.
    Christensson, K
    Mälardalens universitet.
    Malm, Gunilla
    Mälardalens universitet.
    Ekblom, Örjan
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Marcus, Claude
    Karolinska Insitutet.
    High prevalence of cardio-metabolic risk factors among adolescents with intellectual disability.2009In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 98, no 5, p. 853-859Article in journal (Refereed)
    Abstract [en]

    Abstract

    Adults with intellectual disabilities (IDs) have poor lifestyle-related health compared with the general population. Our aim was to study whether such differences are present already in adolescents.

    AIM:

    To compare the prevalence and severity of cardio-metabolic risk factors and cardio-vascular fitness in adolescents with and without IDs.

    METHODS:

    Intellectual disability (ID) students (n = 66) and non-intellectual disability (non-ID) students from practical (non-ID-p) (n = 34) and theoretical (non-ID-t) (n = 56) programmes were recruited from three upper secondary schools. Anthropometric data, blood pressure, body composition, fasting-insulin, fasting-glucose, fasting-lipids and cardio-vascular fitness were measured.

    RESULTS:

    Participants with and without ID differed significantly in the prevalence of cardio-metabolic risk factors with participants with ID having a higher percentage of total fat mass, wider waist circumferences (WCs), lower levels of fat-free mass (FFM), lower bone mineral density (BMD) and higher insulin and homeostasis model assessment of insulin resistance (HOMA) levels and poorer cardio-vascular fitness. The healthiest levels were found in the non-ID-t group compared to the group with ID and the group with non-ID-p in between.

    CONCLUSION:

    The prevalence of cardio-metabolic risk factors and poor cardio-vascular fitness was found to be high in this young population with intellectual disabilities. Measures should be taken to improve the health messages directed towards children and adolescents with intellectual disabilities.

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