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  • 1.
    Boushel, Robert
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology.
    Lundby, Carsten
    Qvortrup, Klaus
    Sahlin, Kent
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Åstrand Laboratory of Work Physiology, Research group for Mitokondriell funktion och metabolisk kontroll.
    Mitochondrial plasticity with exercise training and extreme environments.2014In: Exercise and sport sciences reviews, ISSN 0091-6331, E-ISSN 1538-3008, Vol. 42, no 4, p. 169-74Article in journal (Refereed)
    Abstract [en]

    Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.

  • 2.
    Tonkonogi, Michail
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Sahlin, Kent
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Research group for Mitokondriell funktion och metabolisk kontroll.
    Physical exercise and mitochondrial function in human skeletal muscle.2002In: Exercise and sport sciences reviews, ISSN 0091-6331, E-ISSN 1538-3008, Vol. 30, no 3, p. 129-37Article in journal (Refereed)
    Abstract [en]

    Muscle adaptation to endurance training involves qualitative changes in intrinsic properties of mitochondria. After training, the ADP sensitivity of miitochondrion is decreased whereas the effect of creatine on respiration is increased. This results in an improved control of aerobic energy production. Acute exercise does not adversely affect mitochondrial function.

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