Change search
Refine search result
1 - 13 of 13
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1.
    Ekblom, Elin
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Ståhlberg, Linda
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Hur förhåller sig Fysisk aktivitet och Vo2max till riskfaktorer för hjärt- kärlsjukdomar?2007Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Syfte och frågeställning

    Syftet med denna studie var att studera hur olika nivåer av fysisk aktivitet och maximal syreupptagning (VO2max) förhåller sig till olika riskfaktorer för förtida död i hjärt-kärlsjukdom (CVD). Därutöver var syftet att, om möjligt, utifrån erhållna resultat sammanställa rekommendationer för fysisk aktivitet och VO2max för att erhålla reducerad risk för de studerade riskfaktorerna för CVD.

    Är det VO2max-värdet i sig, som både kan vara genetiskt-, tränings- och sjukdomsbetingat, eller är det den fysiska aktiviteten bakom ett visst VO2max-värde som är av större betydelse för olika riskfaktorer för CVD?

    Metod

    Studien baserades på 1851 svenska kvinnor och män i åldrarna 20-65 år utvalda från ett redan insamlat datamaterial från tre tidigare vetenskapliga studier; LIV90, LIV2000 och Vasaloppsstudien. Den fysiska aktiviteten bestämdes genom en enkätfråga i respektive studie och delades in i tre nivåer. VO2max beräknades via ett submaximalt cykeltest eller mättes via ett maximalt löptest. Tolv välkända riskfaktorer för CVD erhölls utifrån enkätsvar eller medicinska testresultat. För analys av den fysiska aktivitetens och VO2max betydelse för varje riskfaktor, gjordes en binär regressionsanalys med kontroll för fysisk aktivitetsgrad, VO2max samt olika kontrollvariabler. Vid varje analys erhölls en oddskvot med 95 % konfidensintervall som beskrev hur risken att erhålla respektive riskfaktor varierade mellan de olika fysiska aktivitetsgrupperna då VO2max hölls konstant.

    Resultat

    Huvudresultaten i denna studie visade att VO2max hade ett starkare samband än fysisk aktivitet med minskad risk för utfall av enskilda riskfaktorer för CVD. Däremot hade en hög fysisk aktivitetsgrad, motsvarande en belastning som bibehöll/ökade VO2max, liknande betydelse som VO2max för reducering av den generella risken för riskfaktorer för CVD. Fysisk aktivitet på lägre belastningsnivåer uppvisade inte samma signifikanta resultat.

    Slutsats

    Både högre nivåer av fysisk aktivitet och ett högre värde på VO2max har betydelse för reducerad risk för de studerade riskfaktorerna för CVD och i förlängningen utfall av sjukdom i främst CVD. Därför bör hänsyn tas till båda variablerna då hälsopreventiva och hälsopromotiva rekommendationer utformas.

  • 2. Fridén, Jan
    et al.
    Seger, Jan
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Sjöström, Michael
    Ekblom, Björn
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Björn Ekblom's research group.
    Adaptive Response in Human Skeletal Muscle Subjected to Prolonged Eccentric Training1983In: International Journal of Sports Medicine, ISSN 0172-4622, E-ISSN 1439-3964, no 4, p. 177-183Article in journal (Refereed)
    Abstract [en]

    The peripheral adaptation process associated with repeating eccentric training over a longer period of time was studied in m. vastus lateralis of eleven healthy males aged 24 +/- 4 years. The maximal dynamic concentric muscle strength was only slightly improved after 8 weeks of training. However, eccentric work capacity was dramatically increased (375%). A maximal eccentric stint immediately after fulfilled 8 weeks of training caused a selective glycogen depletion from the type 28 fibers. An increased number of type 2C fibers was observed. The ultrastructure analysis showed an essentially well-preserved fine structure. Volume density of mitochondria was somewhat higher in all fiber types after training. Z-band widths were not affected by eccentric training. It is concluded that skeletal musculature adapts itself in a functional manner to the extreme tension demands put on them. Improved coordination and reorganization of the contractile apparatus of muscle fibers are the determining mechanisms of this adaptation.

  • 3. Mogensen, Martin
    et al.
    Bagger, Malene
    Pedersen, Preben
    Fernstrom, Maria
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Sahlin, Kent
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Cycling efficiency in humans is related to low UCP3 content and to type I fibres but not to mitochondrial efficiency2006In: Journal of Physiology, ISSN 0022-3751, E-ISSN 1469-7793, Vol. 571, no 3, p. 669-681Article in journal (Refereed)
    Abstract [en]

    The purpose of this study was to investigate the hypothesis that cycling efficiency in vivo is related to mitochondrial efficiency measured in vitro and to investigate the effect of training status on these parameters. Nine endurance trained and nine untrained male subjects ( , respectively) completed an incremental submaximal efficiency test for determination of cycling efficiency (gross efficiency, work efficiency (WE) and delta efficiency). Muscle biopsies were taken from m. vastus lateralis and analysed for mitochondrial respiration, mitochondrial efficiency (MEff; i.e. P/O ratio), UCP3 protein content and fibre type composition (% MHC I). MEff was determined in isolated mitochondria during maximal (state 3) and submaximal (constant rate of ADP infusion) rates of respiration with pyruvate. The rates of mitochondrial respiration and oxidative phosphorylation per muscle mass were about 40% higher in trained subjects but were not different when expressed per unit citrate synthase (CS) activity (a marker of mitochondrial density). Training status had no influence on WE (trained 28.0 +/- 0.5, untrained 27.7 +/- 0.8%, N.S.). Muscle UCP3 was 52% higher in untrained subjects, when expressed per muscle mass (P < 0.05 versus trained). WE was inversely correlated to UCP3 (r=-0.57, P < 0.05) and positively correlated to percentage MHC I (r= 0.58, P < 0.05). MEff was lower (P < 0.05) at submaximal respiration rates (2.39 +/- 0.01 at 50% ) than at state 3 (2.48 +/- 0.01) but was neither influenced by training status nor correlated to cycling efficiency. In conclusion cycling efficiency was not influenced by training status and not correlated to MEff, but was related to type I fibres and inversely related to UCP3. The inverse correlation between WE and UCP3 indicates that extrinsic factors may influence UCP3 activity and thus MEff in vivo.

  • 4. Mogensen, Martin
    et al.
    Sahlin, Kent
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences, Research group for Mitokondriell funktion och metabolisk kontroll.
    Mitochondrial efficiency in rat skeletal muscle: influence of respiration rate, substrate and muscle type.2006In: Acta Physiologica Scandinavica, ISSN 0001-6772, E-ISSN 1365-201X, Vol. 185, p. 229-236Article in journal (Refereed)
    Abstract [en]

    Aim: To investigate the hypothesis that mitochondrial efficiency (i.e. P/O ratio) is higher in type I than in type II fibres during submaximal rates of respiration.

    Methods: Mitochondria were isolated from rat soleus and extensor digitorum longus (EDL) muscles, representing type I and type II fibres, respectively. Mitochondrial efficiency (P/O ratio) was determined with pyruvate (Pyr) or palmitoyl-L-carnitine (PC) during submaximal (constant rate of ADP infusion) and maximal (Vmax, state 3) rates of respiration and fitted to monoexponential functions.

    Results: There was no difference in Vmax between PC and Pyr in soleus but in EDL Vmax with PC was only 58% of that with Pyr. The activity of 3-hydroxyacyl-CoA dehydrogenase (HAD) was 3-fold higher in soleus than in EDL. P/O ratio at Vmax was 8-9% lower with PC (2.33±0.02 (soleus) and 2.30±0.02 (EDL)) than with Pyr (2.52±0.03 (soleus) and 2.54±0.03 (EDL)) but not different between the two muscles (P>0.05). P/O ratio was low at low rates of respiration and increased exponentially when the rate of respiration increased. The asymptotes of the curves were similar to P/O ratio at Vmax. P/O ratio at submaximal respirations was not different between soleus and EDL neither with Pyr nor with PC.

    Conclusion: Mitochondrial efficiency, as determined in vitro, was not significantly different in the two fibre types neither at Vmax nor at submaximal rates of respiration. The low Vmax for PC oxidation in EDL may relate to low activity of β-oxidation.

  • 5.
    Schantz, Peter
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Capillary supply in heavy-resistance trained non-postural human skeletal muscle1983In: Acta Physiologica Scandinavica, ISSN 0001-6772, E-ISSN 1365-201X, Vol. 117, p. 153.155-Article in journal (Refereed)
  • 6.
    Schantz, Peter
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Plasticity of human skeletal muscle: with special reference to effects of physical training on enzyme levels of the NADH shuttles and phenotypic expression of slow and fast myofibrillar proteins1986Doctoral thesis, comprehensive summary (Other scientific)
  • 7.
    Schantz, Peter
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Billeter, Rudolf
    Henriksson, Jan
    Jansson, Eva
    Training-induced increase in myofibrillar ATPase intermediate fibers in human skeletal muscle1982In: Muscle and Nerve, ISSN 0148-639X, E-ISSN 1097-4598, no 5, p. 628-636Article in journal (Refereed)
  • 8.
    Schantz, Peter
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Björkman, Per
    Sandberg, Mats
    Andersson, Eva
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Movement and muscle activity pattern in wheelchair ambulation by persons with para- and tetraplegia1999In: Scandinavian Journal of Rehabilitation Medicine, ISSN 0036-5505, E-ISSN 1940-2228, Vol. 31, no 2, p. 67-76Article in journal (Refereed)
  • 9.
    Schantz, Peter
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Källman, Mi
    Levels of the NADH shuttle enzymes and cytochrome b5 reductase in human skeletal muscle: effect of strength training1989In: Journal of applied physiology, ISSN 8750-7587, E-ISSN 1522-1601, Vol. 67, no 1, p. 123-127Article in journal (Refereed)
  • 10.
    Schantz, Peter
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Moritani, Toshio
    Karlson, Eddy
    Johansson, Eva
    Lundh, Anna
    Maximal voluntary force of bilateral and unilateral leg extension1989In: Acta Physiologica Scandinavica, ISSN 0001-6772, E-ISSN 1365-201X, Vol. 136, p. 185-192Article in journal (Refereed)
  • 11.
    Schantz, Peter
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Randall-Fox, Emily
    Hutchison, Wallace
    Tydén, Anders
    Åstrand, Per-Olof
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Muscle fibre type distribution, muscle cross-sectional area and maximal voluntary strength in humans1983In: Acta Physiologica Scandinavica, ISSN 0001-6772, E-ISSN 1365-201X, Vol. 117, p. 219-226Article in journal (Refereed)
  • 12.
    Schantz, Peter
    et al.
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Åstrand, Per-Olof
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Physiological characteristics of classical ballet1984In: Medicine and Science in Sports and Exercise, ISSN 0195-9131, Vol. 16, no 5, p. 472-476Article in journal (Refereed)
  • 13. Wibom, Rolf
    et al.
    Hultman, Erik
    Johansson, Mats
    Matherei, Kaj
    Constantin-Teodosiu, Dimitri
    Schantz, Peter
    Swedish School of Sport and Health Sciences, GIH, Department of Sport and Health Sciences.
    Adaptation of mitochondrial ATP-production in human skeletal muscle to endurance training and detraining1992In: Journal of applied physiology, ISSN 8750-7587, E-ISSN 1522-1601, no 73, p. 2004-2010Article in journal (Refereed)
1 - 13 of 13
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf