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No Significant Effect of Prefrontal tDCS on Working Memory Performance in Older Adults.
Aging Research Center, Karolinska Institutet and Stockholm University Stockholm, Sweden..ORCID iD: 0000-0002-6746-0920
2015 (English)In: Frontiers in Aging Neuroscience, E-ISSN 1663-4365, Vol. 7, p. 230-, article id 230Article in journal (Refereed) Published
Abstract [en]

Transcranial direct current stimulation (tDCS) has been put forward as a non-pharmacological alternative for alleviating cognitive decline in old age. Although results have shown some promise, little is known about the optimal stimulation parameters for modulation in the cognitive domain. In this study, the effects of tDCS over the dorsolateral prefrontal cortex (dlPFC) on working memory performance were investigated in thirty older adults. An N-back task assessed working memory before, during and after anodal tDCS at a current strength of 1 mA and 2 mA, in addition to sham stimulation. The study used a single-blind, cross-over design. The results revealed no significant effect of tDCS on accuracy or response times during or after stimulation, for any of the current strengths. These results suggest that a single session of tDCS over the dlPFC is unlikely to improve working memory, as assessed by an N-back task, in old age.

Place, publisher, year, edition, pages
2015. Vol. 7, p. 230-, article id 230
Keywords [en]
N-back, aging, plasticity, tDCS, working memory
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:gih:diva-8020DOI: 10.3389/fnagi.2015.00230PubMedID: 26696882OAI: oai:DiVA.org:gih-8020DiVA, id: diva2:1822422
Available from: 2023-12-22 Created: 2023-12-22 Last updated: 2024-07-04

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Nilsson, Jonna

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