Gymnastik- och idrottshögskolan, GIH

Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Accelerometer derived physical activity and subclinical coronary and carotid atherosclerosis: cross-sectional analyses in 22 703 middle-aged men and women in the SCAPIS study.
Swedish School of Sport and Health Sciences, GIH, Department of Physical Activity and Health.ORCID iD: 0000-0002-3901-7833
Center for Health and Performance, University of Gothenburg, Goteborg, Sweden. ; Institute of Medicine, University of Gothenburg, Goteborg, Sweden..ORCID iD: 0000-0002-8786-0438
Swedish School of Sport and Health Sciences, GIH, Department of Physical Activity and Health.ORCID iD: 0000-0001-6058-4982
Region Västra Götaland, Sahlgrenska University Hospital, Department of Cardiology, Gothenburg, Sweden. ; Department of Molecular and Clinical Medicine, University of Gothenburg, Göteborg, Sweden.
Show others and affiliations
2023 (English)In: BMJ Open, E-ISSN 2044-6055, Vol. 13, no 11, article id e073380Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: The aim included investigation of the associations between sedentary (SED), low-intensity physical activity (LIPA), moderate-to-vigorous intensity PA (MVPA) and the prevalence of subclinical atherosclerosis in both coronaries and carotids and the estimated difference in prevalence by theoretical reallocation of time in different PA behaviours.

DESIGN: Cross-sectional.

SETTING: Multisite study at university hospitals.

PARTICIPANTS: A total of 22 670 participants without cardiovascular disease (51% women, 57.4 years, SD 4.3) from the population-based Swedish CArdioPulmonary bioImage study were included. SED, LIPA and MVPA were assessed by hip-worn accelerometer.

PRIMARY AND SECONDARY OUTCOMES: Any and significant subclinical coronary atherosclerosis (CA), Coronary Artery Calcium Score (CACS) and carotid atherosclerosis (CarA) were derived from imaging data from coronary CT angiography and carotid ultrasound.

RESULTS: High daily SED (>70% ≈10.5 hours/day) associated with a higher OR 1.44 (95% CI 1.09 to 1.91), for significant CA, and with lower OR 0.77 (95% CI 0.63 to 0.95), for significant CarA. High LIPA (>55% ≈8 hours/day) associated with lower OR for significant CA 0.70 (95% CI 0.51 to 0.96), and CACS, 0.71 (95% CI 0.51 to 0.97), but with higher OR for CarA 1.41 (95% CI 1.12 to 1.76). MVPA above reference level, >2% ≈20 min/day, associated with lower OR for significant CA (OR range 0.61-0.67), CACS (OR range 0.71-0.75) and CarA (OR range 0.72-0.79). Theoretical replacement of 30 min of SED into an equal amount of MVPA associated with lower OR for significant CA, especially in participants with high SED 0.84 (95% CI 0.76 to 0.96) or low MVPA 0.51 (0.36 to 0.73).

CONCLUSIONS: MVPA was associated with a lower risk for significant atherosclerosis in both coronaries and carotids, while the association varied in strength and direction for SED and LIPA, respectively. If causal, clinical implications include avoiding high levels of daily SED and low levels of MVPA to reduce the risk of developing significant subclinical atherosclerosis.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2023. Vol. 13, no 11, article id e073380
Keywords [en]
cardiovascular imaging, epidemiology, public health
National Category
Cardiology and Cardiovascular Disease Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medicine/Technology
Identifiers
URN: urn:nbn:se:gih:diva-7971DOI: 10.1136/bmjopen-2023-073380ISI: 001181643400032PubMedID: 37996228OAI: oai:DiVA.org:gih-7971DiVA, id: diva2:1816058
Available from: 2023-11-30 Created: 2023-11-30 Last updated: 2025-02-10

Open Access in DiVA

fulltext(962 kB)71 downloads
File information
File name FULLTEXT01.pdfFile size 962 kBChecksum SHA-512
2cb1d5e9a5c99f5bdf764c7b9ff5d4e09034e43be7721aaf3abd52cafb3354ae1501c97bf4a24f05666c69d4940b1b0de2a0cdce8cce1799a230a36bba76303c
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records

Ekblom Bak, ElinBörjesson, MatsEkblom, Örjan

Search in DiVA

By author/editor
Ekblom Bak, ElinBörjesson, MatsEkblom, Örjan
By organisation
Department of Physical Activity and Health
In the same journal
BMJ Open
Cardiology and Cardiovascular DiseasePublic Health, Global Health, Social Medicine and Epidemiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 71 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 788 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf