Gymnastik- och idrottshögskolan, GIH

Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Increased muscle activity response during startle in children and adolescents with pain in the head, neck and abdomen due to stress
Clintec, Karoliinska Institutet.
Gymnastik- och idrottshögskolan, GIH, Institutionen för fysisk aktivitet och hälsa.ORCID-id: 0000-0001-9040-2158
2020 (engelsk)Konferansepaper, Oral presentation with published abstract (Fagfellevurdert)
Abstract [en]

Background: Headache of stress etiology is a common, worldwide medical problem with high sick leave and large economic consequences. There is a need to improve the understanding of underlying neurobiological processes. Research show that headache of stress etiology often is one symptom in a complex of multiple pains and augmented widespread muscular tension with a specific pattern of tender points (1). 

Objective and Method: We will present in children with recurrent stress related pain, some hormonal changes and electromyography (EMG) data, showing a novel and a missing link, regarding central and peripheral neurophysiological changes of significant importance for better understanding recurrent multiple pain including headache. 

Results: During high acoustic signals, the startle reaction was shown, via EMG, to be potentiated, more easily and more often elicited in several muscles related to the pain, in 19 children with recurrent stress related pain in the head, neck and abdomen, diagnosed according to strict defined criteria (2), and compared to 21 matched controls. Also, higher resting muscle activity was found in these children as well as increased cortisol and decreased oxytocin. 

Conclusion. Stressors evoke stress response for example in the amygdala, which can trigger and potentiate the startle reaction with amplified muscle excitability and tonus. These reactions and the increased cortisol and decreased oxytocin in those children are in accordance with findings of the right dominance of stress in the bi-cameral brain (3). These neurophysiological facts can be of importance for the understanding of clinical manifestation of headache and other pain and must be heeded in the treatment of patients with pain related to stress.  

1.Alfven G, Grillner S, Andersson E. Review of childhood pain highlights the role of negative stress. Acta Paediatr.2019;Jun4.doi:10.1111/apa.14884.

2.Alfvén G, Grillner S, Andersson E. Children with chronic stress-induced recurrent muscle pain have enhanced startle reaction. Eur J Pain.2017;21:1561-1570.

3.Strigo IA, Craig AD. Interoception, homeostatic emotions and sympathovagal balance. 

Philos Trans R Soc Lond B Biol Sci.2016;Nov19;371(1708).

sted, utgiver, år, opplag, sider
2020.
HSV kategori
Forskningsprogram
Medicin/Teknik
Identifikatorer
URN: urn:nbn:se:gih:diva-6493OAI: oai:DiVA.org:gih-6493DiVA, id: diva2:1518093
Konferanse
Brain Disorders Conference, Dubai/online 2020
Tilgjengelig fra: 2021-01-15 Laget: 2021-01-15 Sist oppdatert: 2021-01-15bibliografisk kontrollert

Open Access i DiVA

Alfvén and Andersson Brain Disorders Conference,2020(680 kB)916 nedlastinger
Filinformasjon
Fil FULLTEXT01.pdfFilstørrelse 680 kBChecksum SHA-512
257adb6603b26972b765f741dbd32be5c44dd30397a12d1863e4ffd298732ac1df1cd9879502394f65ef35c9ab674bc9d3cf622b6c194d266e29581fa4ab7b83
Type fulltextMimetype application/pdf

Person

Andersson, Eva

Søk i DiVA

Av forfatter/redaktør
Andersson, Eva
Av organisasjonen

Søk utenfor DiVA

GoogleGoogle Scholar
Totalt: 916 nedlastinger
Antall nedlastinger er summen av alle nedlastinger av alle fulltekster. Det kan for eksempel være tidligere versjoner som er ikke lenger tilgjengelige

urn-nbn

Altmetric

urn-nbn
Totalt: 468 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf