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Adverse outcomes of sick leave due to mental disorders: A prospective study of discordant twin pairs.
Karolinska institutet.
Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, Forskningsgruppen för idrottspsykologi. Karolinska institutet, Stockholms universitet.ORCID-id: 0000-0002-0079-124X
Karolinska institutet.
Karolinska institutet.
2019 (Engelska)Ingår i: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905, Vol. 47, nr 2, s. 127-136Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

AIMS: The aim of this study was to investigate whether sick leave due to different mental disorders increased the risk of reoccurring sick-leave, disability pension and unemployment, taking genetics and shared environment into account.

METHODS: This register-based cohort study contains 2202 discordant twin pairs 18-64 years old, where one twin had sick leave due to a mental disorder 2005-2006. The end of the sick-leave spell was the start of follow-up for both twins. The twins were followed up for reoccurring sick-leave, disability pension and unemployment (> 180 days in a year), until December 2012. Analyses were censored for disability pension, death, emigration and old-age pension. Cox proportional hazards models with time-varying covariates were used to calculate hazard ratios with 95% confidence intervals (CI).

RESULTS: Those with sick leave due to mental disorders had a 3.64 (CI: 3.24-4.08) times higher risk of reoccurring sick-leave within the first two years; after that, hazard ratios were attenuated and explained by genetic factors. The first year, they had 12.24 (CI: 8.11-18.46) times the risk of disability pension. The risk was attenuated but remained at 2.75 (CI: 2.07-3.65) after one year. The risk of unemployment was 1.99 (CI: 1.72-2.31) during the whole follow-up period. The risk of unemployment and disability pension was lower for those with stress-related than other mental disorders, this was less clear for recurrent reoccuring sick-leave.

CONCLUSIONS: Sick leave due to mental disorders increased the risk of reoccurring sick-leave within two years, disability pension and unemployment, independent of genetics and shared environment.

Ort, förlag, år, upplaga, sidor
Sage Publications, 2019. Vol. 47, nr 2, s. 127-136
Nyckelord [en]
Sick Leave, disability insurance, mental disorders, twins, unemployment
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Forskningsämne
Medicin/Teknik
Identifikatorer
URN: urn:nbn:se:gih:diva-5058DOI: 10.1177/1403494817735755ISI: 000462758700007PubMedID: 29032743OAI: oai:DiVA.org:gih-5058DiVA, id: diva2:1154947
Tillgänglig från: 2017-11-06 Skapad: 2017-11-06 Senast uppdaterad: 2019-04-23Bibliografiskt granskad

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Blom, Victoria
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Scandinavian Journal of Public Health
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi

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