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Effect of Q10 supplementation on tissue Q10 levels and adenine nucleotide catabolism during high-intensity exercise.
Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap.
Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, Björn Ekbloms forskningsgrupp.ORCID-id: 0000-0002-4030-5437
Vise andre og tillknytning
1999 (engelsk)Inngår i: International Journal of Sport Nutrition, ISSN 1050-1606, Vol. 9, nr 2, s. 166-80Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The aim of the present study was to investigate the concentration of ubiquinone-10 (Q10), at rest, in human skeletal muscle and blood plasma before and after a period of high-intensity training with or without Q10 supplementation. Another aim was to explore whether adenine nucleotide catabolism, lipid peroxidation, and mitochondrial function were affected by Q10 treatment. Seventeen young healthy men were assigned to either a control (placebo) or Q10-supplementation (120 mg/day) group. Q10 supplementation resulted in a significantly higher plasma Q10/total cholesterol level on Days 11 and 20 compared with Day 1. There was no significant change in the concentration of Q10 in skeletal muscle or in isolated skeletal muscle mitochondria in either group. Plasma hypoxanthine and uric acid concentrations increased markedly after each exercise test session in both groups. After the training period, the postexercise increase in plasma hypoxanthine was markedly reduced in both groups, but the response was partially reversed after the recovery period. It was concluded that Q10 supplementation increases the concentration of Q10 in plasma but not in skeletal muscle.

sted, utgiver, år, opplag, sider
1999. Vol. 9, nr 2, s. 166-80
HSV kategori
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URN: urn:nbn:se:gih:diva-540PubMedID: 10362453OAI: oai:DiVA.org:gih-540DiVA, id: diva2:159895
Tilgjengelig fra: 2009-02-10 Laget: 2009-02-10 Sist oppdatert: 2018-01-13bibliografisk kontrollert

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