Gymnastik- och idrottshögskolan, GIH

Change search
Link to record
Permanent link

Direct link
Publications (10 of 15) Show all publications
Regan, C., Heiland, E. G., Ekblom, Ö., Tarassova, O., Kjellenberg, K., Larsen, F. J., . . . Helgadóttir, B. (2023). Acute effects of nitrate and breakfast on working memory, cerebral blood flow, arterial stiffness, and psychological factors in adolescents: Study protocol for a randomised crossover trial.. PLOS ONE, 18(5), Article ID e0285581.
Open this publication in new window or tab >>Acute effects of nitrate and breakfast on working memory, cerebral blood flow, arterial stiffness, and psychological factors in adolescents: Study protocol for a randomised crossover trial.
Show others...
2023 (English)In: PLOS ONE, E-ISSN 1932-6203, Vol. 18, no 5, article id e0285581Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Inorganic nitrate has been shown to acutely improve working memory in adults, potentially by altering cerebral and peripheral vasculature. However, this remains unknown in adolescents. Furthermore, breakfast is important for overall health and psychological well-being. Therefore, this study will investigate the acute effects of nitrate and breakfast on working memory performance, task-related cerebral blood flow (CBF), arterial stiffness, and psychological outcomes in Swedish adolescents.

METHODS: This randomised crossover trial will recruit at least 43 adolescents (13-15 years old). There will be three experimental breakfast conditions: (1) none, (2) low-nitrate (normal breakfast), and (3) high-nitrate (concentrated beetroot juice with normal breakfast). Working memory (n-back tests), CBF (task-related changes in oxygenated and deoxygenated haemoglobin in the prefrontal cortex), and arterial stiffness (pulse wave velocity and augmentation index) will be measured twice, immediately after breakfast and 130 min later. Measures of psychological factors and salivary nitrate/nitrite will be assessed once before the conditions and at two-time points after the conditions.

DISCUSSION: This study will provide insight into the acute effects of nitrate and breakfast on working memory in adolescents and to what extent any such effects can be explained by changes in CBF. This study will also shed light upon whether oral intake of nitrate may acutely improve arterial stiffness and psychological well-being, in adolescents. Consequently, results will indicate if nitrate intake from beetroot juice or if breakfast itself could acutely improve cognitive, vascular, and psychological health in adolescents, which can affect academic performance and have implications for policies regarding school meals.

TRIAL REGISTRATION: The trial has been prospectively registered on 21/02/2022 at https://doi.org/10.1186/ISRCTN16596056. Trial number: ISRCTN16596056.

Place, publisher, year, edition, pages
Public Library of Science (PLoS), 2023
National Category
Nutrition and Dietetics
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-7653 (URN)10.1371/journal.pone.0285581 (DOI)001050599900048 ()37205681 (PubMedID)
Funder
Knowledge Foundation, 20180040
Note

This project is supported by The Knowledge Foundation https://www.kks.se/ (20180040; ÖE, GN), and the following companies: COOP Sverige, IKEA, Skandia, Skanska, Generation Pep, and Konsumentföreningen Stockholm.

Available from: 2023-06-20 Created: 2023-06-20 Last updated: 2024-01-26
Kjellenberg, K., Heiland, E. G., Tarassova, O., Fernström, M., Nyberg, G., Ekblom, M., . . . Ekblom, Ö. (2023). Effects of physical activity breaks on working memory and oxygenated hemoglobin in adolescents: Results from the AbbaH teen study. In: : . Paper presented at ArtScientific 2023, Frankfurt, Germany, May 5-6, 2023.
Open this publication in new window or tab >>Effects of physical activity breaks on working memory and oxygenated hemoglobin in adolescents: Results from the AbbaH teen study
Show others...
2023 (English)Conference paper, Oral presentation with published abstract (Other academic)
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medicine/Technology; Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-7797 (URN)
Conference
ArtScientific 2023, Frankfurt, Germany, May 5-6, 2023
Funder
Knowledge FoundationSkandias Stiftelse Idéer för livet
Note

Partners är: IKEA, Kronprinsessparets stiftelse/Generation Pep, Skanska, Coop, KFS

Available from: 2023-09-15 Created: 2023-09-15 Last updated: 2023-10-03Bibliographically approved
Fernström, M., Heiland, E. G., Kjellenberg, K., Pontén, M., Tarassova, O., Nyberg, G., . . . Ekblom, Ö. (2023). Effects of prolonged sitting and physical activity breaks on measures of arterial stiffness and cortisol in adolescents. Acta Paediatrica, 112(5), 1011-1018
Open this publication in new window or tab >>Effects of prolonged sitting and physical activity breaks on measures of arterial stiffness and cortisol in adolescents
Show others...
2023 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 112, no 5, p. 1011-1018Article in journal (Refereed) Published
Abstract [en]

Aim

In adults, prolonged periods of sitting have been linked to acute negative effects on vascular structure and function. The aim of this study was to evaluate the acute effects of physical activity (PA) breaks during prolonged sitting on arterial stiffness, cortisol and psychological factors in adolescents.

Methods

Adolescents underwent different short (3-min) breaks starting every 20 min, during 80 min of sitting on three separate days. Breaks were (A) social seated breaks (SOC), (B) low-intensity simple resistance activity PA breaks (SRA) and (C) moderate-intensity step-up PA breaks (STEP). The arterial stiffness measures were augmentation index (AIx), AIx@75 and pulse wave velocity (PWV). Cortisol was measured from saliva. Psychological factors were self-reported.

Results

Eleven girls and six boys (average age 13.6 ± 0.7 years) participated, with average baseline heart rates of 72 ± 11 bpm, systolic/diastolic blood pressure 111 ± 7/64 ± 6 mmHg and cortisol 10.9 ± 5.8 nmoL/L. PWV, cortisol and psychological factors did not change after any of the conditions. AIx@75 increased significantly (4.9 ± 8.7–9.2 ± 13.2) after the STEP intervention compared with SOC and SRA (time × condition p < 0.05).

Conclusion

Arterial stiffness increased after prolonged sitting with frequent, short step-up activity breaks. The results indicate potential important intensity-dependent effects of physical activity on vascular regulation in youth.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023
Keywords
AIx, PWV, activity breaks, adolescents, arterial stiffness, cortisol
National Category
Cardiac and Cardiovascular Systems Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-7487 (URN)10.1111/apa.16702 (DOI)000933114700001 ()36740937 (PubMedID)
Funder
Knowledge Foundation, 20160040
Note

Additional funding information: COOP Sweden, IKEA, Skandia, Skanska, Generation Pep, and Stockholm Consumer Cooperative Society

Available from: 2023-02-14 Created: 2023-02-14 Last updated: 2024-01-26Bibliographically approved
Kjellenberg, K., Heiland, E. G., Tarassova, O., Fernström, M., Nyberg, G., Ekblom, M., . . . Ekblom, Ö. (2023). Short, frequent physical activity breaks improve working memory in adolescents during prolonged sitting (AbbaH teen study). In: : . Paper presented at The International Society of Behavioral Nutrition and Physical Activity (ISBNPA), Uppsala, Sweden, June 15-18, 2023.
Open this publication in new window or tab >>Short, frequent physical activity breaks improve working memory in adolescents during prolonged sitting (AbbaH teen study)
Show others...
2023 (English)Conference paper, Oral presentation with published abstract (Other academic)
Abstract [en]

Purpose: Physical activity breaks in schools have been suggested as a promising strategy to acutely improve cognitive performance in children and adolescents. Most previous studies have explored the effects of single physical activity bouts, but they are infeasible in a school setting (e.g. long duration/high-intensity or requiring equipment/space). Further, studies investigating the underlying physiological mechanisms in adolescents arel acking. Therefore, the aim of this study was to investigate the effects of short, frequent physical activity breaks of different intensities on adolescents’ working memory (WM) and cerebral blood flow (CBF) during prolonged sitting.

Methods: This randomized crossover study was performed in adolescents (13-15 years of age). In 80-minute sessions, one of the following types of breaks was performed four times in three minutes durations on three different days: simple resistance training (SRA), step-up at a pre-determined pace (STEP), or remaining seated (SOCIAL). Before and after each session, WM (accuracy and reaction time during the 1,2,3-back test) were measured, with simultaneous measurement of task-related CBF (assessed by prefrontal oxygenation using functional near-infrared spectroscopy). Analysis of CBF is ongoing and will be presented at the conference.

Results: A total of 17 students participated (mean age 13.6 years, 11 girls). In the most demanding task (3-back) the following results were seen: improvement in reaction time following SRA (-30.1, p=0.04) and STEP (-34.3 ms, p=0.05) and no improvement following prolonged sitting. We also found a moderating effect (p <0.01) of WM performance at baseline (using a mean split), such that students with poor WM significantly improved their accuracy and reaction time following the higher-intensity breaks (STEP) while students with high performance did not.

Conclusion: We found that implementing physical activity breaks of both moderate and high intensities was beneficial for WM performance. For students with low WM performance, high-intensity breaks were more beneficial. Implementing physical activity breaks during periods of prolonged sitting, such as long school classes could improve the students’ cognitive performance. However, future studies should investigate if these breaks are feasible, acceptable, and beneficial to implement in the school setting.

National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medicine/Technology; Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-7798 (URN)
Conference
The International Society of Behavioral Nutrition and Physical Activity (ISBNPA), Uppsala, Sweden, June 15-18, 2023
Funder
Knowledge FoundationSkandias Stiftelse Idéer för livetThe Kamprad Family FoundationSwedish ESF Council (Council of the European Social Fund in Sweden)
Note

Partners är: IKEA, Kronprinsessparets stiftelse/Generation Pep, Storytel, SATS, Permobil

Available from: 2023-09-15 Created: 2023-09-15 Last updated: 2023-10-13Bibliographically approved
Heiland, E. G., Kjellenberg, K., Tarassova, O., Fernström, M., Nyberg, G., Ekblom, M., . . . Ekblom, Ö. (2022). ABBaH teens: Activity Breaks for Brain Health in adolescents. Trials, 23(1), Article ID 22.
Open this publication in new window or tab >>ABBaH teens: Activity Breaks for Brain Health in adolescents
Show others...
2022 (English)In: Trials, E-ISSN 1745-6215, Vol. 23, no 1, article id 22Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Physical activity breaks are widely being implemented in school settings as a solution to increase academic performance and reduce sitting time. However, the underlying physiological mechanisms suggested to improve cognitive function from physical activity and the frequency, intensity, and duration of the breaks remain unknown. This study will investigate the effects of frequent, short physical activity breaks during prolonged sitting on task-related prefrontal cerebral blood flow, cognitive performance, and psychological factors. Additionally, the moderating and mediating effects of arterial stiffness on changes in cerebral blood flow will be tested.

METHODS: This is a protocol for a randomized crossover study that will recruit 16 adolescents (13-14 years old). Participants will undergo three different conditions in a randomized order, on three separate days, involving sitting 80 min with a different type of break every 17 min for 3 min. The breaks will consist of (1) seated social breaks, (2) simple resistance activities, and (3) step-up activities. Before and after the 80-min conditions, prefrontal cerebral blood flow changes will be measured using functional near-infrared spectroscopy (primary outcome), while performing working memory tasks (1-, 2-, and 3-back tests). Arterial stiffness (augmentation index and pulse wave velocity) and psychological factors will also be assessed pre and post the 80-min interventions.

DISCUSSION: Publication of this protocol will help to increase rigor in science. The results will inform regarding the underlying mechanisms driving the association between physical activity breaks and cognitive performance. This information can be used for designing effective and feasible interventions to be implemented in schools.

TRIAL REGISTRATION: www.ClinicalTrials.gov , NCT04552626 . Retrospectively registered on September 21, 2020.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2022
Keywords
Cerebral blood flow, Cognitive function, Physical activity breaks, Sedentary, fNIRS
National Category
Neurology
Research subject
Medicine/Technology; Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-6901 (URN)10.1186/s13063-021-05972-5 (DOI)000739964400002 ()34991692 (PubMedID)
Projects
Hjärnhälsa i skolan Delprojekt II: Skolor i högstadiet med förlängda dagar med fysisk aktivitet och läxläsning
Funder
Knowledge Foundation, 20160040
Note

Projektet samfinansieras av KK-stiftelsen, Coop AB, Skanska, IKEA, Generation Pep, Skandia och Konsumentföreningen Stockholm samt GIH

Available from: 2022-01-10 Created: 2022-01-10 Last updated: 2024-01-17
Heiland, E. G., Tarassova, O., Fernström, M., English, C., Ekblom, Ö. & Ekblom, M. (2021). Frequent, Short Physical Activity Breaks Reduce Prefrontal Cortex Activation but Preserve Working Memory in Middle-Aged Adults: ABBaH Study.. Frontiers in Human Neuroscience, 15, Article ID 719509.
Open this publication in new window or tab >>Frequent, Short Physical Activity Breaks Reduce Prefrontal Cortex Activation but Preserve Working Memory in Middle-Aged Adults: ABBaH Study.
Show others...
2021 (English)In: Frontiers in Human Neuroscience, E-ISSN 1662-5161, Vol. 15, article id 719509Article in journal (Refereed) Published
Abstract [en]

Prolonged sitting is increasingly common and may possibly be unfavorable for cognitive function and mood. In this randomized crossover study, the effects of frequent, short physical activity breaks during prolonged sitting on cognitive task-related activation of the prefrontal cortex were investigated. The effects on working memory, psychological factors, and blood glucose were also examined, and whether arterial stiffness moderated prefrontal cortex activation. Thirteen subjects (mean age 50.5 years; eight men) underwent three 3-h sitting conditions, interrupted every 30-min by a different 3-min break on separate, randomized-ordered days: seated social interactions (SOCIAL), walking (WALK), or simple resistance activities (SRA). Arterial stiffness was assessed at baseline. Before and after each 3-h condition, psychological factors (stress, mood, sleepiness, and alertness) were assessed through questionnaires and functional near-infrared spectroscopy (fNIRS) was used to measure changes in prefrontal oxygenated hemoglobin (Oxy-Hb), indicative of cortical activation, while performing working memory tasks [1- (baseline), 2-, and 3-back]. Blood glucose levels were continuously measured throughout the conditions. Results revealed no significant changes in Oxy-Hb during the 2-back compared with the 1-back test in any condition, and no time-by-condition interactions. During the 3-back test, there was a significant decrease in Oxy-Hb compared with the 1-back after the WALK condition in the right prefrontal cortex, but there were no time-by-condition interactions, although 3-back reaction time improved only in the WALK condition. Mood and alertness improved after the WALK condition, which was significantly different from the SOCIAL condition. Arterial stiffness moderated the effects, such that changes in Oxy-Hb were significantly different between WALK and SOCIAL conditions only among those with low arterial stiffness. Blood glucose during the interventions did not differ between conditions. Thus, breaking up prolonged sitting with frequent, short physical activity breaks may reduce right prefrontal cortex activation, with improvements in some aspects of working memory, mood, and alertness. Clinical Trial Registration:www.ClinicalTrials.gov, identifier NCT04137211.

Place, publisher, year, edition, pages
Frontiers Media S.A., 2021
Keywords
cerebral blood flow, cognition, exercise, functional near-infrared spectroscopy, sedentary
National Category
Neurosciences
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-6803 (URN)10.3389/fnhum.2021.719509 (DOI)000701370000001 ()34602995 (PubMedID)
Projects
Fysisk aktivitet och hälsosamma hjärnfunktioner bland kontorsarbetare. Delprojekt 2 Akuta interventioner
Available from: 2021-10-06 Created: 2021-10-06 Last updated: 2024-02-27
Fernberg, U., Fernström, M. & Hurtig-Wennlöf, A. (2021). Higher Total Physical Activity is Associated with Lower Arterial Stiffness in Swedish, Young Adults: The Cross-Sectional Lifestyle, Biomarkers, and Atherosclerosis Study. Vascular Health and Risk Management, 17, 175-185
Open this publication in new window or tab >>Higher Total Physical Activity is Associated with Lower Arterial Stiffness in Swedish, Young Adults: The Cross-Sectional Lifestyle, Biomarkers, and Atherosclerosis Study
2021 (English)In: Vascular Health and Risk Management, ISSN 1176-6344, E-ISSN 1178-2048, Vol. 17, p. 175-185Article in journal (Refereed) Published
Abstract [en]

Purpose: Arterial stiffness describes the rigidity of the arterial walls and is associated withrisk factors for cardiovascular disease (CVD). Arterial stiffness predicts future events andmortality, and the predictive value is stronger in younger versus older subjects. The aims ofthe present study were, firstly, to present data on physical activity (PA) and time spentsedentary, in the population of Swedish, young adults. Secondly, to explore the associationbetween PA and arterial stiffness.

Material and Methods: Self-reported healthy, non-smoking, Swedish, young adults, 18–25years old, participated in the cross-sectional Lifestyle, Biomarkers and Atherosclerosis(LBA) study. The daily PA was objectively measured with an accelerometer for 1 week.Of the 834 participants, 658 individuals had valid registrations. The arterial stiffness measures, pulse wave velocity (PWV) and augmentation index (AIx) were measured withapplanation tonometry.

Results: Women were on overall more physically active than men, they spent 214 min/dayin light PA (LPA) compared to men who spent 202 min/day. Women took significantly moresteps per day than men, 7796 vs 7336 steps/day, and spent less time sedentary, 523 min/day,compared to men who spent 547 min/day sedentary. In total, 76% of the individuals spent onaverage at least 30 minutes per day in the recommended moderate and vigorous PA (MVPA).Lower arterial stiffness was associated with more MVPA and total PA in the total population.

Conclusion: We conclude that in this age group of young, self-reported healthy adults18–25 years, it is important to highlight the health-enhancing possibilities of time spent inphysical activity on the vascular function, measured as PWV and AIx. It is of high relevancein a public health perspective to expand preventive efforts beyond the high-risk groups andencourage young adults to be physically active.

Place, publisher, year, edition, pages
DovePress, 2021
Keywords
accelerometry, atherosclerosis, healthy population, pulse wave analysis, pulse wave velocity
National Category
Cardiac and Cardiovascular Systems
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-6667 (URN)10.2147/VHRM.S283211 (DOI)000646223600001 ()33953561 (PubMedID)
Available from: 2021-05-04 Created: 2021-05-04 Last updated: 2021-05-27
Heiland, E. G., Ekblom, Ö., Tarassova, O., Fernström, M., English, C. & Ekblom, M. (2020). ABBaH: Activity Breaks for Brain Health: A Protocol for a Randomized Crossover Trial. Frontiers in Human Neuroscience, 14, Article ID 273.
Open this publication in new window or tab >>ABBaH: Activity Breaks for Brain Health: A Protocol for a Randomized Crossover Trial
Show others...
2020 (English)In: Frontiers in Human Neuroscience, E-ISSN 1662-5161, Vol. 14, article id 273Article in journal (Refereed) Published
Abstract [en]

Introduction: Extended periods of sitting may have detrimental effects on brain health. However, the effects of breaking up prolonged sedentary periods with frequent, short physical activity bouts on mechanisms to improve brain health remain unclear. Therefore, this study aims to investigate the immediate effects of uninterrupted sitting and frequent, short bouts of physical activity on cerebral blood flow and cognitive function in the prefrontal cortex in middle-aged adults. Methods: This is a protocol article to describe a randomized crossover study. We will collect data from 13 healthy adults, aged between 40 and 60 years old, with a body mass index <35 kg/m(2). Participants will be required to come into the laboratory on three occasions, sit for 3 h, and perform a different type of break for 3 min every 30 min at each visit in a random order, being either: (1) a social break; (2) brisk walk on a treadmill; or (3) simple resistance activities. Before and after each experimental condition, cerebral blood flow (primary outcome) will be measured using functional near-infrared spectroscopy (fNIRS), with short-separation channels, and working memory (1-, 2-, and 3-back on the computer) will be assessed. The following additional secondary outcomes will be collected: psychological factors (questionnaires); arterial stiffness; salivary cortisol levels; and blood glucose levels. Conclusion: The results from this randomized crossover study will determine the effects of uninterrupted sitting and frequent, short bouts of physical activity on cerebral blood flow and cognitive performance. Publication of this study protocol emphasizes the importance of registration and publication of protocols in the field of sedentary behavior research.

Place, publisher, year, edition, pages
Frontiers Media S.A., 2020
Keywords
physical activity breaks, sedentary, cerebral blood flow, cognitive function, fNIRS
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-6270 (URN)10.3389/fnhum.2020.00273 (DOI)000556365000001 ()32760263 (PubMedID)
Projects
Fysisk aktivitet och hälsosamma hjärnfunktioner bland kontorsarbetare. Delprojekt 2 Akuta interventioner
Available from: 2020-08-21 Created: 2020-08-21 Last updated: 2024-02-27
Fernström, M., Fernberg, U. & Hurtig-Wennlöf, A. (2020). The importance of cardiorespiratory fitness and sleep duration in early CVD prevention: BMI, resting heart rate and questions about sleep patterns are suggested in risk assessment of young adults, 18–25 years: The cross-sectional lifestyle, biomarkers and atherosclerosis (LBA) study.. BMC Public Health, 20, Article ID 1715.
Open this publication in new window or tab >>The importance of cardiorespiratory fitness and sleep duration in early CVD prevention: BMI, resting heart rate and questions about sleep patterns are suggested in risk assessment of young adults, 18–25 years: The cross-sectional lifestyle, biomarkers and atherosclerosis (LBA) study.
2020 (English)In: BMC Public Health, E-ISSN 1471-2458, Vol. 20, article id 1715Article in journal (Refereed) Published
Abstract [en]

Background

Cardiorespiratory fitness (CRF) and sleep habits are lifestyle factors with potential to prevent cardiovascular disease (CVD). CVD is the leading cause of death worldwide. It is therefore important to establish a healthy lifestyle at a young age. In the Lifestyle, Biomarkers and Atherosclerosis (LBA) study we have examined 834 healthy non-smoking adults, aged 18–25 years. The general purpose of the LBA study was to study the effect of lifestyle on traditional biomarkers known to influence CVD risk. The aims of the present study were to evaluate sleep habits of young adult women and men participating in the LBA study, and to compare the importance of sleep and other lifestyle habits on clinically relevant biomarkers for CVD. An additional aim was to find easy and reliable non-invasive biomarkers to detect young adults with increased risk of developing CVD later in life.

Methods

The participants had previously been examined for lifestyle factors, biomarkers and CVD risk score. They filled in a validated computerized questionnaire about their general physical and mental health. The questionnaire included questions on sleep duration and experienced quality of sleep.

Results

In total 27% of the young adult participants reported difficulties falling asleep or experienced troubled sleep with frequent awakenings per night. The experienced troubled sleep was not related to a higher CVD risk score, but sleep quality and duration were correlated. Shorter sleep duration was significantly associated to higher body mass index (BMI), body fat (%), homeostasis model assessment of insulin resistance (HOMA-IR) and CVD risk. The modifiable lifestyle factor with the highest odds ratio (OR) for CVD risk was CRF. Sleep duration was the second most influential lifestyle factor, more important than moderate- and vigorous physical activity (MVPA) and food habits. Correlations between CRF and heart rate (HR), (P < 0.01) and HOMA-IR and BMI (P < 0.01) were observed, indicating that BMI and resting HR in combination with questions about sleep patterns are easy and reliable non-invasive biomarkers to detect young adults who need counselling on a healthy lifestyle.

Conclusion

Decreased sleep duration in combination with decreased CRF, in young adults, is a serious health issue.

Place, publisher, year, edition, pages
BioMed Central, 2020
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-6376 (URN)10.1186/s12889-020-09801-3 (DOI)000594990500009 ()33198684 (PubMedID)
Available from: 2020-11-16 Created: 2020-11-16 Last updated: 2023-08-28Bibliographically approved
Fernberg, U., Op 't Roodt, J., Fernström, M. & Hurtig-Wennlöf, A. (2019). Body composition is a strong predictor of local carotid stiffness in Swedish, young adults - the cross sectional Lifestyle, biomarkers, and atherosclerosis study.. BMC Cardiovascular Disorders, 19(1), Article ID 205.
Open this publication in new window or tab >>Body composition is a strong predictor of local carotid stiffness in Swedish, young adults - the cross sectional Lifestyle, biomarkers, and atherosclerosis study.
2019 (English)In: BMC Cardiovascular Disorders, ISSN 1471-2261, E-ISSN 1471-2261, Vol. 19, no 1, article id 205Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Obesity has nearly tripled worldwide during the last four decades, especially in young adults, and is of growing concern since it is a risk factor for cardiovascular diseases (CVD). We explored how different body composition measurements are associated with intima media thickness (cIMT) and local stiffness in the common carotid artery, in a subsample of healthy, young women and men, from the Swedish Lifestyle, Biomarkers, and Atherosclerosis (LBA) Study.

METHODS: From the LBA study, a subsample of 220 randomly selected, self-reported healthy individuals, 18-25 years old, were collected for the automatized local stiffness measurements; arterial distensibility, Young's elastic modulus, and β stiffness index. Blood pressure and mean arterial pressure (MAP) was measured using automatic blood pressure equipment. Body mass index (BMI) was calculated, waist circumference was measured, and percentage of body fat assessed using an impedance body composition analyzer. The carotid artery was scanned by ultrasound and analyzed using B-mode edge wall tracking. cIMT was measured and local stiffness measurements were calculated with carotid blood pressure, measured with applanation tonometry.

RESULTS: No association was found between cIMT and body composition. Local carotid stiffness was associated with body composition, and women had less stiff arteries than men (p < 0.001). Of the local stiffness measurements, arterial distensibility had the strongest associations with body composition measurements in both women and men (p < 0.05). Multiple regression analyses showed that BMI in women and BMI and percentage of body fat in men had the highest impact on arterial distensibility (p < 0.01 in both women and men).

CONCLUSIONS: Arterial distensibility was the local stiffness measurement with the strongest associations to different body composition measurements, in both women and men. In this age group, body composition measurements seem to be stronger predictors of common carotid arterial stiffness than MAP, and is a convenient way of detecting young adults who need cardiovascular risk follow-up and lifestyle counseling.

Place, publisher, year, edition, pages
BioMed Central, 2019
Keywords
Arterial distensibility, Arterial stiffness, Body composition, Carotid artery, Cross-sectional study, Epidemiological, Intima media thickness, Young adults
National Category
Cardiac and Cardiovascular Systems
Research subject
Medicine/Technology
Identifiers
urn:nbn:se:gih:diva-5826 (URN)10.1186/s12872-019-1180-6 (DOI)000483032600001 ()31455254 (PubMedID)
Available from: 2019-08-30 Created: 2019-08-30 Last updated: 2019-09-17
Projects
Physical Activity for Healthy Brain Functions in School Youth [KK 20180040]; Swedish School of Sport and Health Sciences, GIH; Publications
Hoy, S., Larsson, H., Kjellenberg, K., Nyberg, G., Ekblom, Ö. & Helgadóttir, B. (2024). Gendered relations? Associations between Swedish parents, siblings, and adolescents' time spent sedentary and physically active. Frontiers in Sports and Active Living, 6, Article ID 1236848. Heiland, E. G., Kjellenberg, K., Tarassova, O., Nyberg, G., Ekblom, M., Ekblom, Ö. & Helgadóttir, B. (2023). Acute effects of nitrate and breakfast on working memory and cerebral blood flow in adolescents: a randomized crossover trial. In: : . Paper presented at The International Society of Behavioral Nutrition and Physical Activity (ISBNPA), Uppsala, Sweden, June 15-18, 2023. Regan, C., Heiland, E. G., Ekblom, Ö., Tarassova, O., Kjellenberg, K., Larsen, F. J., . . . Helgadóttir, B. (2023). Acute effects of nitrate and breakfast on working memory, cerebral blood flow, arterial stiffness, and psychological factors in adolescents: Study protocol for a randomised crossover trial.. PLOS ONE, 18(5), Article ID e0285581. Yman, J., Helgadóttir, B., Kjellenberg, K. & Nyberg, G. (2023). Associations between organised sports participation, general health, stress, screen-time and sleep duration in adolescents.. Acta Paediatrica, 112(3), 452-459Nyberg, G., Helgadóttir, B., Kjellenberg, K. & Ekblom, Ö. (2023). COVID-19 and unfavorable changes in mental health unrelated to changes in physical activity, sedentary time, and health behaviors among Swedish adolescents: A longitudinal study.. Frontiers In Public Health, 11, Article ID 1115789. Helgadóttir, B., Fröberg, A., Kjellenberg, K., Ekblom, Ö. & Nyberg, G. (2023). COVID-19 induced changes in physical activity patterns, screen time and sleep among Swedish adolescents - a cohort study.. BMC Public Health, 23(1), Article ID 380. Kjellenberg, K., Heiland, E. G., Tarassova, O., Fernström, M., Nyberg, G., Ekblom, M., . . . Ekblom, Ö. (2023). Effects of physical activity breaks on working memory and oxygenated hemoglobin in adolescents: Results from the AbbaH teen study. In: : . Paper presented at ArtScientific 2023, Frankfurt, Germany, May 5-6, 2023. Fernström, M., Heiland, E. G., Kjellenberg, K., Pontén, M., Tarassova, O., Nyberg, G., . . . Ekblom, Ö. (2023). Effects of prolonged sitting and physical activity breaks on measures of arterial stiffness and cortisol in adolescents. Acta Paediatrica, 112(5), 1011-1018Helgadóttir, B., Fröberg, A., Kjellenberg, K., Ekblom, Ö. & Nyberg, G. (2023). Has COVID-19 led to changes in physical activity patterns, screen time and sleep among Swedish adolescents?: A cohort study. In: : . Paper presented at The International Society of Behavioral Nutrition and Physical Activity (ISBNPA), Uppsala, Sweden, June 15-18, 2023. Thedin Jakobsson, B., Hoy, S., Lunde, C. & Larsson, H. (2023). Physical Activity during the School Day: A Case Study in Swedish School for Students with Special Needs.. In: : . Paper presented at European Educational Research Association (ECER) Glasgow, den 22- 25 Augusti 2023..
E-PABS - a centre of Excellence in Physical Activity, healthy Brain functions and Sustainability [20210002 01 H]; Swedish School of Sport and Health Sciences, GIH; Publications
Hoy, S., Larsson, H., Kjellenberg, K., Nyberg, G., Ekblom, Ö. & Helgadóttir, B. (2024). Gendered relations? Associations between Swedish parents, siblings, and adolescents' time spent sedentary and physically active. Frontiers in Sports and Active Living, 6, Article ID 1236848. Heiland, E. G., Kjellenberg, K., Tarassova, O., Nyberg, G., Ekblom, M., Ekblom, Ö. & Helgadóttir, B. (2023). Acute effects of nitrate and breakfast on working memory and cerebral blood flow in adolescents: a randomized crossover trial. In: : . Paper presented at The International Society of Behavioral Nutrition and Physical Activity (ISBNPA), Uppsala, Sweden, June 15-18, 2023. Regan, C., Heiland, E. G., Ekblom, Ö., Tarassova, O., Kjellenberg, K., Larsen, F. J., . . . Helgadóttir, B. (2023). Acute effects of nitrate and breakfast on working memory, cerebral blood flow, arterial stiffness, and psychological factors in adolescents: Study protocol for a randomised crossover trial.. PLOS ONE, 18(5), Article ID e0285581. Farias, L., Nyberg, G., Helgadóttir, B. & Andermo, S. (2023). Adolescents' experiences of a school-based health promotion intervention in socioeconomically advantaged and disadvantaged areas in Sweden: a qualitative process evaluation study.. BMC Public Health, 23(1), Article ID 1631. Larsson, L. E., Wang, R., Cederholm, T., Wiggenraad, F., Rydén, M., Hagman, G., . . . Thunborg, C. (2023). Association of Sarcopenia and Its Defining Components with the Degree of Cognitive Impairment in a Memory Clinic Population.. Journal of Alzheimer's Disease, 96(2), 777-788Yman, J., Helgadóttir, B., Kjellenberg, K. & Nyberg, G. (2023). Associations between organised sports participation, general health, stress, screen-time and sleep duration in adolescents.. Acta Paediatrica, 112(3), 452-459Wu, J., Xiong, Y., Xia, X., Orsini, N., Qiu, C., Kivipelto, M., . . . Wang, R. (2023). Can dementia risk be reduced by following the American Heart Association's Life's Simple 7?: A systematic review and dose-response meta-analysis.. Ageing Research Reviews, 83, Article ID 101788. Nyberg, G., Helgadóttir, B., Kjellenberg, K. & Ekblom, Ö. (2023). COVID-19 and unfavorable changes in mental health unrelated to changes in physical activity, sedentary time, and health behaviors among Swedish adolescents: A longitudinal study.. Frontiers In Public Health, 11, Article ID 1115789. Helgadóttir, B., Fröberg, A., Kjellenberg, K., Ekblom, Ö. & Nyberg, G. (2023). COVID-19 induced changes in physical activity patterns, screen time and sleep among Swedish adolescents - a cohort study.. BMC Public Health, 23(1), Article ID 380. Kjellenberg, K., Heiland, E. G., Tarassova, O., Fernström, M., Nyberg, G., Ekblom, M., . . . Ekblom, Ö. (2023). Effects of physical activity breaks on working memory and oxygenated hemoglobin in adolescents: Results from the AbbaH teen study. In: : . Paper presented at ArtScientific 2023, Frankfurt, Germany, May 5-6, 2023.
ExStress - Exercise Intensity on Brain and Mental Health in Stress; Swedish School of Sport and Health Sciences, GIH
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-9526-2967

Search in DiVA

Show all publications